CD34 Antikörper (Biotin)

Produktnummer ABIN488155

Dieses Maus Monoklonal-Antikörper erkennt spezifisch CD34 in FACS. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CD34 Antikörper (Biotin) (ABIN488155)

Target: CD34

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD34 Antikörper ist konjugiert mit Biotin

Applikation: Flow Cytometry (FACS)

Klon: 4H11

Produktdetails anti-CD34 Antikörper (Biotin)

Spezifität: This antibody reacts with Class III epitope on CD34 (Mucosialin), a 110-115 kDa monomeric transmembrane phosphoglycoprotein expressed on hematopoietic progenitors cells and on the most pluripotential stem cells, it is gradually lost on progenitor cells. The antibody 4H11[APG] completely blocks binding of Class II antibody QBEnd10 and Class III antibodies BIRMA K3 and 8G12 on KG1a cell line.

Kreuzreaktivität (Details): Species reactivity (tested):Human

Produktmerkmale: Synonyms: Hematopoietic progenitor cell marker, Hematopoietic progenitor cell antigen CD34

Immunogen: Permanent human cell line derived from peripheral leucocytes of a patient suffering fromchronic myeloid leukaemia

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Indirect immunofluorescence analysis by Flow cytometry (1: 200 as starting point.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer. Avoid repeatedfreezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu CD34

Target: CD34

Andere Bezeichnung: CD34

Hintergrund: CD34 is a highly glycosylated monomeric 111-115 kDa surface protein, which is present on many stem cell populations. It is a well established stem cell marker, though its expression on human hematopoietic stem cells is reversible. CD34 probably serves as a surface receptor that undergoes receptor-mediated endocytosis and regulates adhesion, differentiation and proliferation of hematopoietic stem cells and other progenitors. CD34 expression is likely to represent a specific state of hematopoietic development that may have altered adhering properties with expanding and differentiating capabilities in both in vitro and in vivo conditions.Synonyms: Hematopoietic progenitor cell antigen CD34, Hematopoietic progenitor cell marker

Gen-ID: 947

UniProt: P28906